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In addition, we assessed the effects of losartan and placebo on the following secondary end points: a composite of morbidity and mortality from cardiovascular causes, proteinuria, and the rate of progression of renal disease.
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It is clear that low levels of 25(OH)D are found in both healthy persons and those with autoimmune or chronic inflammatory diseases.
OLETF rats until 25 weeks of age (0.
Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes.
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These observations may have important clinical implications in terms of minimizing potential adverse effects and maximizing patient convenience and long-term adherence to therapy.
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Documenting lower-extremity sensory neuropathy is useful in patients who present with foot ulcers because decreased sensation limits the patient's ability to protect the feet and ankles.
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Morbus Diureticus in the Elderly: Epidemic Overuse of a Widely Applied Group of Drugs.
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Patients with diabetes should be screened annually for DPN using tests such as pinprick sensation, vibration perception (using a 128-Hz tuning fork), 10-g monofilament pressure sensation at the distal plantar aspect of both great toes and metatarsal joints, and assessment of ankle reflexes.
Treatment with angiotensin II receptor (AR) antagonists should be discontinued permanently if angioedema develops in association with therapy.
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Observe patients receiving thiazide therapy for clinical signs of fluid or electrolyte imbalance: hyponatremia, hypochloremic alkalosis, and hypokalemia.
Potassium Salts: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers.
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In case, you have any of these conditions, you may need a dose adjustment or some special tests for observing kidney disease, liver disease, congestive heart failure or if you are dehydrated.
The benefit of intensive glycemic control in this type 1 diabetic cohort has recently been shown to persist for several decades ().
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Systematic Review of Pharmacogenomics in the Renin-Angiotensin System.
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The antihypertensive effect of angiotensin II receptor antagonists, including olmesartan medoxomil may be attenuated by NSAIDs including selective COX-2 inhibitors.
Ion exchange resins: Staggering the dosage of hydrochlorothiazide and ion exchange resins (e.
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PAD, are common and are major causes of morbidity and disability in people with diabetes.
Persistence and adherence to antihypertensive treatment in relation to initial prescription.
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Both olmesartan medoxomil and amlodipine, at the recommended starting dose, produced significantly greater reductions from baseline in mean 24-h ambulatory DBP compared with placebo (-7.
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Nutrition Practice Guidelines for Type 1 Diabetes Mellitus positively affect dietitian practices and patient outcomes.
The association may result from shared risk factors between type 2 diabetes and cancer (obesity, age, physical inactivity) but may also be due to hyperinsulinemia or hyperglycemia ().
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ANCOVA model was used for all other comparisons of cuff blood pressure, and for comparisons of ambulatory blood pressure.
Integrating new approaches for clinical development: translational research and relative effectiveness.
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